FA2H Polyclonal Antibody, 100ul Immune Repertoire Sequencing This gene represents a retrogene

This gene represents a retrogene of RNA binding motif protein| X-linked (RBMX)| which is located on chromosome X

where it stimulates transcription of liver-expressed genes

Once activated by a ligand| the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription

The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum

FA2H Polyclonal Antibody, 100ul Immune Repertoire Sequencing This gene represents a retrogeneThis gene encodes a protein that catalyzes the synthesis of 2 hydroxysphingolipids, a subset of sphingolipids that contain 2 hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2 hydroxylation of the N acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy