IRE1 Alpha Monoclonal Antibody, 100ul Adeno-associated Virus Packaging PTTG1IP (pituitary tumor-transforming 1 interacting

PTTG1IP (pituitary tumor-transforming 1 interacting protein) encodes a single-pass type I integral membrane protein

Mutations in this gene are associated with the autosomal dominant disorder| encephalopathy| lethal| due to defective mitochondrial and peroxisomal fission (EMPF)

The ectodomain

2006 [PubMed 16326147])

IRE1 Alpha Monoclonal Antibody, 100ul Adeno-associated Virus Packaging PTTG1IP (pituitary tumor-transforming 1 interactingThe protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum based stress signals.