MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis Mutations at this locus have

Mutations at this locus have been linked to autosomal recessive deafness

It is unclear whether it acts as a GTPase

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

or in stimulating catalytic functions of other subunits during initiation

MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis Mutations at this locus haveThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase mediated signaling cascade. It phosphorylates and thus activates MAPK14 p38 MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the